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Gene name:
Areg(Sdgf);
Protein name:
Amphiregulin(AR);
Alternative:
Schwannoma-derived growth factor(SDGF);
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
The immature precursor interacts with CNIH.
Function:
Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Subcellular Location:
Membrane Single-pass membrane protein
Protein Attributes:
Sequence length:
248
Sequence:
50:
MRTPLLPLAR | SVLLLLVLGS | GHYAAALELN | DPSSGKGESL | SGDHSAGGLE |
100:
LSVGREVSTI | SEMPSGSELS | TGDYDYSEEY | DNEPQISGYI | IDDSVRVEQV |
150:
IKPKKNKTEG | EKSTEKPKRK | KKGGKNGKGR | RNKKKKNPCT | AKFQNFCIHG |
200:
ECRYIENLEV | VTCNCHQDYF | GERCGEKSMK | THSEDDKDLS | KIAVVAVTIF |
248:
VSAIILAAIG | IGIVITVHLW | KRYFREYEGE | TEERRRLRQE | NGTVHAIA
3D Structure:
N/A
Predicted Eptitope:
N/A
Related Databases
STRING:
10090.ENSMUSP00000031325
SMR:
P31955
String:
P31955
UniGene:
Mm.8039
KEGG:
mmu:11839
Uniprot:
P31955